I’ve only just started working on HIV, so I’m still currently starting up a lot of my experiments, and haven’t got many results yet. At the moment I’m trying to understand the patterns of mutation left in the genome after different types of transmission (spread) – for example, a population where everyone is equally likely to infect another, versus a population where there’s a more infectious group and a less infectious group. To do this, I use a computer to simulate a real epidemic for each situation, including sequence data, and then look at how they’re different at the end. Once I understand this, I can look at real data and infer what is going on in the human population.
Comments
Keith commented on :
I’m afraid I don’t work on HIV so I think this one is all Bethany 🙂