At the moment, not a lot! I’ve only just started working on HIV, so I’m currently starting up a lot of my experiments, and haven’t got many results yet. Currently, I’m trying to understand the patterns of mutation left in the genome after different types of transmission (spread) – for example, a population where everyone is equally likely to infect another, versus a population where there’s a more infectious group and a less infectious group. To do this, I use a computer to simulate a real epidemic for each situation, including sequence data, and then look at how they’re different at the end. Once I understand this, I can look at real data and infer what is going on in the human population.
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